first_imgAntidiabétique et cancer du poumon : exploration d’un nouveau mode de préventionMonde – Un antidiabétique pourrait prévenir l’apparition du cancer du poumon.Des chercheurs américains se sont penchés sur les moyens de prévenir le cancer du poumon. Si arrêter de fumer semble être la meilleure solution, il faut néanmoins trouver d’autres pistes. À lire aussiRisques liés à Internet : le gouvernement vient en aide aux parentsEn menant des expérimentations sur des rongeurs, cette équipe de scientifiques a découvert les propriétés de la metformine. Celle-ci était déjà connue pour son effet sur d’autres pathologies. A la base, c’est un traitement couramment utilisé pour lutter contre le diabète de type 2 et disponible sous forme générique. Il serait donc peu coûteux. En outre, il est sans risque et ses effets semblent très prometteurs. En effet, les souris qui n’ont pas reçu le traitement mais des doses de tabac ont été 100% à développer un cancer du poumon. Chez celles qui ont bénéficié du traitement par voie orale, le risque a été réduit de 40 à 50% et chez celles qui l’ont reçu par injection, de 72%. Le mécanisme reposerait sur l’activation d’une enzyme neutralisant une protéine responsable du développement des cellules cancéreuses, supposent les chercheurs. Leurs travaux sont publiés dans la revue Cancer Prevention Research. Le 3 septembre 2010 à 10:45 • Emmanuel Perrinlast_img read more

first_img There is no question robots will eventually join the workforce.But will the manager’s dream—cleaning sewers without complaint—be the workers’ nightmare?Matt Beane, a faculty member at UC Santa Barbara’s Technology Management program, describes a utopia where automated employees handle “dirty, dangerous, and dull” tasks, like shutting down a leaky nuclear reactor or inspecting electronic components.There’s just one catch: This paradise, in which human nor cyborg is more valued than the other, doesn’t exist.“The problem is that installing robots often makes the jobs around them worse,” Beane wrote in a piece for Wired.“Use a robot for aerial reconnaissance, and remote pilots end up bored. Use a robot for surgery, and surgical trainees end up watching, not learning,” he said. “Use a robot to transport materials, and workers … can no longer interact with and learn from their customers. Use a robot to farm, and farmers end up barred from repairing their own tractors.”And he should know: Beane spent the last seven years studying these dynamics in the field.A research affiliate with MIT’s Institute for the Digital Economy, Beane studies deviance in work involving artificial intelligence—specifically robotics. His field research includes robotic surgery, materials transport, and telepresence in healthcare, elder care, and knowledge work.For two years, Beane watched automated medical procedures in top-tier U.S. hospitals, where “most nurses and surgical assistants were bored out of their skulls.”As he describes it, the process of robotic surgery is slow, slow, slow, fast, then very slow. While a surgeon operates the bot from a control console, everyone else stands around, twiddling their thumbs and checking Facebook.“There’s not a lot to do, but you always have to come ready,” Beane said. “Compared to open surgery, it’s clean, safe, and dull work.”The same can be said across other industries, where the installation of cyborgs has led to less challenging jobs for humans, with fewer opportunities to learn.There are pluses, of course: People can direct their attention elsewhere, to other projects or employees. But it’s not easy recognizing these opportunities.“Getting these clues takes careful, boots-on-the-ground attention to the entire work system as it changes,” according to Beane. “Using them to guide a broader work redesign can cost more than a typical robotic install—and not all roboticization is worth equal attention.“But not doing this work guarantees an outcome we can’t afford: a future of degrading work,” he said.Worried about the future of your livelihood? Check out Geek’s list of 11 robots that are going to steal your jobs to find out if you’re in danger.Let us know what you like about Geek by taking our survey. Stay on target Evan Rachel Wood Just As Disturbed by Humanoid Sophia As Everyone ElseMIT’s Thread-Like Robot Slides Through Blood Vessels In the Brain last_img read more

first_imgRio Ferdinand recently made a shocking revelation about his struggles with binge drinking in the early years of his football career.Ferdinand was part of the Hammers academy in 95′ before a switch to Leeds United where his displays caught the attention of Sir Alex Ferguson in what was a big money move for a young central defender.And it was during his time at Upton Park – the Hammers’ former home – that he says his drinking reached levels that he now looks back on with regret.In an interview cited by the Mirror, the former England defender turned pundit said: “I used to get through a load when I was younger. I could probably get through eight, nine, ten [pints].Harry Maguire, Manchester UnitedLiverpool legend Nicol slams Harry Maguire’s Man United form Andrew Smyth – September 14, 2019 Steve Nicol believes Harry Maguire has made some “horrendous mistakes” recently, and has failed to find his best form since joining Manchester United.“Then I’d move on to the vodkas. I could go through loads. I could go all day drinking then wake up and go again when I was younger.“I always say to people who ask if I have any regrets about playing, I wouldn’t have drunk alcohol.“When I was younger… I was a lunatic. When I was at west ham… elements of my career are a blur. People talk about certain times in the games and I just sit and nod my head. I haven’t got a clue what they’re talking about. I don’t remember.”last_img read more

first_imgPeter Crouch believes Tottenham are very much still in the mix for the Premier League title, despite being behind Manchester City and Liverpool.Mauricio Pochettino’s side currently trail the joint-leaders by five points heading into Sunday’s home game against Leicester City.However, due to the absences of Harry Kane and Dele Alli, hopes of an unexpected title challenge are low at North London.But Crouch, who played for Spurs as a striker between 2009 to 2011 and scored 24 goals in 93 appearances, believes people would be foolish to rule out his old club.“It’s madness, given there is so much football to play,” Crouch wrote on his Daily Mail column.“It is also madness to rule out Tottenham, who are right in there as well.”He added “I know bookmakers have them as third favourites but, for the points they have racked up, you simply cannot take them out of the discussion.“There is a trait about modern football that I don’t particularly like – the need to make instant and definitive predictions.“I say I don’t like it, but I also have to admit it’s something of which I have been guilty.”The former England international pointed out that both City and Liverpool have suffered slips ups this season and suggested there could be more exciting twists and turns left.Harry Maguire, Manchester UnitedLiverpool legend Nicol slams Harry Maguire’s Man United form Andrew Smyth – September 14, 2019 Steve Nicol believes Harry Maguire has made some “horrendous mistakes” recently, and has failed to find his best form since joining Manchester United.“The title race is the subject that is prompting everyone to put their necks on the line and the past fortnight has been especially revealing for rash judgments,” continued Crouch.“Manchester City lost at Newcastle and the title was Liverpool’s to lose. Then Liverpool drew at home to Leicester, City beat Arsenal and West Ham took points off Liverpool.“Now we are in the position, following City’s win at Goodison Park, when everyone is saying it is over to Pep Guardiola’s side again.“The Premier League is the best league in the world because anyone can beat anyone and you have to keep this in mind.”Crouch now plays for Burnley in the Premier League after sealing a switch from Stoke City in the January transfer window.How do we fare against The Foxes? 🦊A look at the numbers ahead of Sunday’s @premierleague clash. 👀📹: @KumhoTyreUK pic.twitter.com/Teotlxvoi7— Tottenham Hotspur (@SpursOfficial) February 9, 2019last_img read more

first_img SEATTLE — In five previous outings this season, Marcus Mariota was wearing a baseball cap and sending in signals from the Oregon sideline by the time the fourth quarter rolled around.When the Ducks were finally pushed on Saturday, Mariota and his teammates gave an emphatic response that added another notch to a decade of dominance over their rivals to the north.Mariota threw for 366 yards and three touchdowns, added another 88 yards and one TD rushing, and the second-ranked Ducks beat No. 16 Washington 45-24 to extend their winning streak in the series to 10.“Guys were able to battle. I definitely think we’re a four-quarter type team, we just haven’t had a reason to play four quarters,” Oregon running back Byron Marshall said. “So the fact we got the first one under our belt to answer everyone’s questions is good.”Mariota’s passing was nearly spotless, he used his legs to make the Huskies pay when throwing options were covered, and he was easily the best player on the field. Mariota completed 24 of 31 passes, and ran another 13 times. He threw touchdowns of 4 and 3 yards to Bralon Addison and a 65-yarder to Josh Huff on Oregon’s first possession of the second half. Huff had to be carted to the locker room with an apparent right leg injury in the first half, only to come back after halftime and burn the Huskies secondary. Oregon’s Wade Keliikipi (92) sacks Washington quarterback Keith Price in the second half of an NCAA college football game, Saturday, Oct. 12, 2013, in Seattle. Oregon won 45-24. (AP Photo/Elaine Thompson)last_img read more

first_imgROZSYPNE, Ukraine — World leaders called for an immediate cease-fire in eastern Ukraine today and demanded speedy access for international investigators to the crash site of the Malaysia Airlines jetliner shot down over the country’s battlefields.The strong words came amid the contrasting images of emergency workers and off-duty coal miners fanning out across picturesque sunflower fields searching for charred pieces of wreckage from the Boeing 777.The attack Thursday afternoon killed 298 people from nearly a dozen nations — including vacationers, students and a large contingent of scientists heading to an AIDS conference in Australia.President Barack Obama called for an immediate cease-fire between Ukrainian government forces and pro-Russia separatists. He also called for a credible investigation.“The eyes of the world are on eastern Ukraine, and we are going to make sure that the truth is out,” Obama said at the White House.U.S. intelligence authorities said a surface-to-air missile brought down Malaysia Airlines Flight 17 as it traveled from Amsterdam to Kuala Lumpur. U.S. Ambassador Samantha Power told the U.N. Security Council in New York on Friday the missile was likely fired from a rebel-held area near the Russian border.last_img read more

first_imgAlmost a third (63%) of male employee respondents with young children are interested in taking shared parental leave (SPL) in the future, according to research by My Family Care and the Women’s Business Council.The Shared parental leave: where are we now? report, which surveyed 200 employers and 1,000 working parents, also found that 40% of employee respondents feel that shared parental leave is encouraged by their employer.The research also found:87% of male employee respondents would like to take longer leave in order to be more involved in parenting their child.Half (50%) of male employee respondents believe that opting to take shared parental leave would be perceived negatively in the workplace.57% of female employee respondents think that their partner’s career would be negatively affected if they took SPL.More than half (55%) of female employee respondents would prefer to take the full period of leave themselves, while 60% of male respondents believe that their partner would prefer to take the full leave themselves.44% of female respondents want to take a shorter period of leave for career purposes.77% of employer respondents have enhanced maternity pay.Almost two-thirds (65%) of employer respondents have enhanced paternity pay.Emer Timmons (pictured), chair of the Men as Change Agents working group at the Women’s Business Council, said: “The findings from My Family Care highlights the important role that business can play in raising awareness of the opportunity to take SPL.“One year on, we can see that some fathers have embraced the opportunity to spend time with their young families but that there is still a long way to go for others.”Ben Black, founder of My Family Care, added: “The key thing for businesses is to help their employees combine work and family, by providing them with choices and enabling them to carry on with their careers while having a family.“More and more we’re going to hear fantastic stories of fathers, at senior levels, who have taken shared parental leave, and once these stories filter through, and the notion of sharing leave in this way becomes ‘normal’, then it will be accepted practice and that 1% will gradually increase.“Of course, all change takes time and while it hasn’t so far been the cultural change that many were clamouring for, I suspect with many [organisations] enhancing paternity leave, momentum will grow.”last_img read more

first_img Tags Share your voice RIP the great Rutger Hauer: an intense, deep, genuine and magnetic actor that brought truth, power and beauty to his films. My personal favorites: Flesh + Blood, Eureka, The Hitcher, Blade Runner, Ladyhawke and Blind Fury. pic.twitter.com/1F2Via3mLY— Guillermo del Toro (@RealGDT) July 24, 2019 Comments In a 2017 interview with Radio Times, Hauer discussed the speech, crediting director Ridley Scott for letting him tweak the script.”I kept two lines, because I thought they were poetic,” he said, referring to the lines mentioning attack ships and C-beams.  “I thought they belonged to this character, because somewhere in his digital head he has poetry, and knows what it is. He feels it! And while his batteries are going, he comes up with the two lines.”The speech has been praised and quoted innumerable times since then. Singer David Bowie even quoted it on a card he sent for his half-brother’s funeral, Rolling Stone reports.”I was hoping to come up with one line where Roy, because he understands he has very little time, expresses one bit of the DNA of life that he’s felt,” Hauer told Radio Times. “How much he liked it. Only one life.”Hauer was a natural brunette, but his hair was bleached a whitish-blond for his Blade Runner role. “The bleach hurts,” he told the Sarasota Herald-Tribune in 1981. “Now I know why some suffer to be blond.” He is survived by his wife Ineke. The couple was together for 50 years.  The actor began his theater career in the Netherlands, made several films in Germany, and then moved to American movies with the Sylvester Stallone 1981 film Nighthawks, following it up with Blade Runner.  In that 1981 Sarasota Herald-Tribune article, he said a Hollywood agent suggested he change his name to something more familiar to Americans, but he declined. “If you’re good enough, people will remember your name,” he told the paper. In addition to Blade Runner, other films included Ladyhawke, The Hitcher, Confessions of a Dangerous Mind and Batman Begins. He won a Golden Globe award for the TV movie Escape from Sobibor.As news of Hauer’s death spread, both his famous friends and regular fans alike remembered him online. Director Guillermo del Toro called him “an intense, deep, genuine and magnetic actor that brought truth, power and beauty to his films.”  Many of Rutger Hauer’s more memorable roles saw him playing villains, but I’ve always really loved his performance in Hobo With a Shotgun. It’s a gory grindhouse throwback at the end of the day, but Hauer really elevates it with his heartbreaking work as the title character. pic.twitter.com/7Yyl336Tw8— John Squires (@FreddyInSpace) July 24, 2019center_img 3 TV and Movies Originally published July 24, 10:40 a.m. PT.  RIP Rutger Hauer 🙏 I had the honor of working with him in ‘Surviving The Game’ https://t.co/o2cQgBF9l2— ICE T (@FINALLEVEL) July 24, 2019 NurPhoto/Corbis via Getty Images Actor Rutger Hauer, best known for playing Roy Batty in the original 1982 Blade Runner film, has died at 75. A charity he established, the Rutger Hauer Starfish Association, announced that Hauer died on July 19 at his home after a short illness. The association is a nonprofit focusing on helping children and pregnant women with HIV/AIDS. His funeral was held Wednesday, Variety reports. A representative for Hauer didn’t immediately respond to a request for comment. Hauer delivered the famed “tears in rain” death monologue in Blade Runner, a speech he helped tweak for the screen. “I’ve seen things you people wouldn’t believe,” Hauer says as Batty, a replicant being hunted by Harrison Ford’s character Rick Deckard. “Attack ships on fire off the shoulder of Orion. I watched C-beams glitter in the dark near the Tannhäuser Gate. All those moments will be lost in time, like tears in rain. Time to die.” This is one of my favorite outtakes that we dug up during the BLADE RUNNER Final Cut restoration: Rutger Hauer giving such a tremendous performance, that even Harrison Ford (who was understandably fed-up with the shoot at this point) gave Rutger an affectionate “atta boy.” https://t.co/Cmnx4X0uE1— Charles de Lauzirika (@Lauzirika) July 24, 2019last_img read more

first_imgMaruti Suzuki, country’s largest car maker is reportedly working on a new hatchback for India, suggests a new report.Financial Express claims that Maruti Suzuki, India’s trusted name for small cars is gearing up to launch a new Alto K10 hatchback in the country by 2015. According to the report, the car is likely to take design cues from Maruti’s successful Celerio and would feature automated manual transmission (AMT) technology.”The new Alto K10 will be launched around January 2015. The design has completely been changed and it will now offer more space, more modern interiors as well as the AMT auto gear technology,” FE quoted a source close to the development .Alto K10, the small car offering of Maruti has been a successful endevour in the domestic market as well as the export markets like Africa and South America. Hyundai Eon and Datsun Go are the main rivals of the Alto K10 in India. Recently, Hyundai has launched a new model of Eon in the sub-continent market.Under the hood, the new Alto K10 is likely to pack 998cc 3 pot motor of the Celelrio, which can churn out 68 PS of max power and 90 Nm of torque. Previous reports had suggested that the vehicle would feature larger and more stylish swept-back headlamps, new engine grille with chrome outline, reworked front bumper and the new rounded bonnet.Maruti is also expected to launch the SX4 replacement Ciaz in the country by the end of this year. The Ciaz, which was first seen at the Delhi Auto Expo 2014, is based on the Suzuki Authentics concept car and is likely to come with 1.3 liter Multijet diesel or 1.4 liter K Series petrol engine of Ertiga. The car will be pitted against Hyundai Verna, Honda City and Volkswagen Vento in the sub-continent and is expected to fall in the price brackets of ₹7.2 lakh to ₹10.5 lakh.[ED:VS]last_img read more

first_imgGazipur mayor MA MannanThe High Court has stayed the suspension order of pro-BNP Gazipur City Corporation mayor MA Mannan for three months.An HC bench comprising justice Syed Mohammad Dastagir Hossain justice Mohammad Ataur Rahman Khan delivered the stay order a day after he was suspended for the third time.Mannan’s lawyer Mahbub Uddin Khokon said from now on, there is no legal bar to take up office again for the mayor.The apex court passed with the verdict after the Gazipur mayor on Sunday filed a writ petition challenging his dismissal. On Saturday last, a letter of mayor Mannan’s suspension issued by the Local Government Division reached the Gazipur City Corporation office around 3:30pm half an hour after Mannan’s left the office.[No legal bar for Gazipur mayor to take office]Half an hour after that, the authorities appointed Awami League Ward Councillor Asadur Raman Kiron as an acting mayor.Earlier on 12 June last year, the ACC filed a case against pro-BNP mayor Mannan and Golam Kibria with Joydebpur police station on charge of misappropriating over Tk 4.9 million of the city corporation by creating 999 unsigned fake vouchers.ACC submitted the charge sheet with Gazipur special judge court on 12 January this year last. Later on 18 January, the court accepted the charge sheet.last_img read more

first_imgKolkata: Forward Bloc leader Reboti Mohan Bhattacharya was arrested on alleged charges of helping a person get a loan of Rs 1 crore without “proper documents” from a cooperative bank at Suri in Birbhum.Bhattacharya, who is the district committee president of the party and also a member of the state committee, was arrested on Tuesday night based on a complaint lodged with Suri police station.He was the chairman of Birbhum Zilla Cooperative Bank till 2012. The present chairman of the bank, Nurul Islam, raised the allegation and based on the same the complaint was lodged with the police station. Also Read – Speeding Jaguar crashes into Merc, 2 B’deshi bystanders killedIt was alleged that Bhattacharya had used his influence to get the loan sanctioned for a person well known to him. There was also allegation of sanctioning the loan without properly going through the documents, which are essential to sanction a loan.It has been learnt that the complaint was lodged after it was claimed that the present members of the cooperative bank have found out certain discrepancies while sanctioning the loan worth Rs 1 crore.The police have initiated a probe in this connection, based on the allegations raised against Bhattacharya. They are also going through the documents in this connection and have taken the statement of the bank authorities as well.The police will also speak to some more erstwhile members of the bank authorities in this connection. Other leaders of his party have, however, claimed that he had been framed.last_img read more

first_imgNews | Prostate Cancer | January 18, 2017 PI-RADS Named Best Clinical Research Paper by European Urology Prostate Imaging Reporting and Data System provides standardized reporting scheme January 18, 2017 — An article promoting standardized imaging efforts to improve diagnosis and treatment of prostate cancer has been selected as the best clinical research paper published in European Urology. “PI-RADS Prostate Imaging — Reporting and Data System: 2015, Version 2,” written by members of the MR Prostate Imaging Reporting and Data System (PI-RADS) Steering Committee, was published January 2016 in the official journal of the European Association of Urology (EAU). The article provides updated information for the acquisition and standardized interpretation and reporting of multiparametric magnetic resonance imaging (MRI) of the prostate to detect potentially life-threatening cancers.“Since the publication of this paper last year, the newest version of PI-RADS has been welcomed with open arms and rapidly implemented by the prostate cancer medical community. The positive impact has been tremendous on both clinical care and research concerning the risk of clinically significant prostate cancer that may require biopsy and treatment,” said Jeffrey C. Weinreb, M.D., FACR, co-chair of the MR Prostate Imaging Reporting and Data System (PI-RADS) Steering Committee. Written for medical professionals, the online document along with the European Urology article represent an international scientific consensus, he added. Weinreb noted the steering committee was honored that its efforts received this international distinction. The award will be presented at the EAU annual meeting in March.The American College of Radiology (ACR) formed a joint effort with AdMeTech Foundation and the European Society of Urogenital Radiology (ESUR) to expedite the transfer of high-quality MRI from laboratories to patients to address a major need in prostate cancer care — reducing unnecessary biopsies and treatment.Members of the steering committee and authors of the journal article include Weinreb; Jelle O. Barentsz, M.D., Ph.D. (co-chair); Peter L. Choyke, M.D., FACR; François Cornud, M.D.; Masoom A. Haider, M.D.; Katarzyna J. Macura, M.D., Ph.D., FACR; Daniel Margolis, M.D.; Mitchell D. Schnall, M.D., Ph.D., FACR; Clare M. Tempany, M.D.; Harriet C. Thoeny, M.D.; and Sadhna Verma, M.D.For more information: www.europeanurology.comReferencesWeinreb, J.C., Barentsz, J.O., Choyke, P.L., Cornud, F., et al. “PI-RADS Prostate Imaging – Reporting and Data System: 2015, Version 2,” European Urology. Published Jan. 1, 2016. DOI: 10.1016/j.eururo.2015.08.052 FacebookTwitterLinkedInPrint分享 News | Clinical Decision Support | July 18, 2019 Johns Hopkins Named Qualified Provider-led Entity to Develop Criteria for Diagnostic Imaging On June 30, 2019, the Centers for Medicare & Medicaid Services (CMS) announced the Johns Hopkins University School… read more Technology | Interventional Radiology | August 16, 2019 Profound Medical Receives U.S. FDA 510(k) Clearance for Tulsa-Pro Profound Medical Corp. announced it has received 510(k) clearance from the U.S. Food and Drug Administration (FDA) to… read more Video Player is loading.Princess Margaret Cancer Center uses machine learning to create automated treatment plansPlay VideoPlayMuteCurrent Time 0:00/Duration 3:22Loaded: 4.83%Stream Type LIVESeek to live, currently playing liveLIVERemaining Time -3:22 Playback Rate1xChaptersChaptersDescriptionsdescriptions off, selectedCaptionscaptions settings, opens captions settings dialogcaptions off, selectedAudio Trackdefault, selectedFullscreenThis is a modal window.Beginning of dialog window. 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News | Artificial Intelligence | July 26, 2019 Progenics Pharmaceuticals Collaborating With Veterans Affairs on AI Cancer Imaging Research Program Oncology company Progenics Pharmaceuticals Inc. announced their collaboration with the Veterans Affairs Greater Los… read more Key Topics for Radiology Administrators at AHRA 2019Video Player is loading.Play VideoPlayMuteCurrent Time 0:00/Duration 7:33Loaded: 2.15%Stream Type LIVESeek to live, currently playing liveLIVERemaining Time -7:33 Playback Rate1xChaptersChaptersDescriptionsdescriptions off, selectedCaptionscaptions settings, opens captions settings dialogcaptions off, selectedAudio Trackdefault, selectedFullscreenThis is a modal window.Beginning of dialog window. Escape will cancel and close the window.TextColorWhiteBlackRedGreenBlueYellowMagentaCyanTransparencyOpaqueSemi-TransparentBackgroundColorBlackWhiteRedGreenBlueYellowMagentaCyanTransparencyOpaqueSemi-TransparentTransparentWindowColorBlackWhiteRedGreenBlueYellowMagentaCyanTransparencyTransparentSemi-TransparentOpaqueFont Size50%75%100%125%150%175%200%300%400%Text Edge StyleNoneRaisedDepressedUniformDropshadowFont FamilyProportional Sans-SerifMonospace Sans-SerifProportional SerifMonospace SerifCasualScriptSmall CapsReset restore all settings to the default valuesDoneClose Modal DialogEnd of dialog window.Close Modal DialogThis is a modal window. This modal can be closed by pressing the Escape key or activating the close button.last_img read more

first_imgThe ultimate guide to Christmas in SingaporeThe ultimate guide to Christmas in SingaporeA Wizarding World at Changi Airport | November – mid February 2019The magical and magnificent Wizarding World of Harry Potter has descended upon Changi Airport this festive season! Visitors of all ages can enjoy exploring iconic locations from the series, from Diagon Alley to Hogsmeade Village, and if lucky, will catch a glance of Hogwarts in the distance. There’s more to do than just sightseeing – get spellbound by daily live shows and simulated snowfall at the Terminal 3 Departure Hall. changiairport.com/wizardingworldholidayChristmas Wonderland, Gardens By The Bay | November 2018 – 26 December 2018The annual Christmas Wonderland is a must-see highlight of Singapore’s exciting year-end celebrations. Watch the gardens come alive with large-scale illuminations at night, with festivities taking up the space of almost five soccer fields. Marvel at the stunning luminarie light sculptures that are handmade by craftsmen from Italy and take a picture under Asia’s tallest luminarie Christmas tree. You will also find festive markets, carnival rides and ice-skating under the stars.www.visitsingapore.com/festivals-events-singapore/annual-highlights/christmas-wonderland/Christmas on a Great Street | November – 1 January 2019Stroll along Orchard Road and take in the festive sights of Christmas as buildings are decorated with Christmas décor and the streets are strung with thousands of fairy lights to create a magical wonderland. Christmas On A Great Street is a surreal world of fun, food and fashion with colourful displays of décor, designs and lights. www.orchardroad.org/christmasDisney’s Magical Moments | November – 1 January 2019For the first time, the famous Orchard Road is decked out in spectacular lights inspired by Disney’s beloved characters. Children can expect to be captivated by the Disney-themed displays and nightly live performances, as icons like Cinderella, Elsa (Frozen) and Woody (Toy Story) come to life. Along the way, check out The Great Christmas Village’s pop-up at Ngee Ann City’s Civic Plaza, which is filled with delectable food and drink, merchandise stands and amusement rides that will keep you enthralled for hours. www.disney.sg/disney-magical-momentsA Universal Christmas | November – 1 January 2019This year, Universal Studios Singapore comes alive in true north-pole fashion to celebrate the festive season! Stroll around Elf Town to meet some of Santa’s helpers and witness the stunning Santa’s Snowy Sleigh Parade! Put on your dancing shoes and boogie along to your favourite Christmas hits at King Julien’s tropical Merry Mambo Madagascar Christmas Party! You can also sing classic Christmas hits with Betty Boop and Marilyn Monroe.www.rwsentosa.com/en/shows-and-events/christmas/universal-christmasGlowing Ocean, S.E.A Aquarium | November 2018 – 6 January 2019S.E.A Aquarium transforms into a mystical water wonderland with 40,000 glowing sea creatures, scuba Santa and mesmerising light installations. Visitors can explore five multi-sensory zones from the radiant lights of the Crazy Colourful Corals zone to the Abyssal zone, which uses holograms to discover the weird and wonderful deep sea fish living in pitch black darkness. www.rwsentosa.com/en/shows-and-events/christmas/sea-aquariumChristmas at ArtScience Museum | 2 December 2018 – 6 January 2019Sketch Christmas, the festive addition to the museum’s permanent FUTURE WORLD: Where Art Meets Science exhibition is happening at the ArtScience Museum. The latest festive installation is where visitors can enjoy 10 new interactive art works and see Santa deliver presents at the click of a button. www.marinabaysands.com/museumSource = Visit Singaporelast_img read more

close-up details, decried as false and defamatory in an initial lawsuit last month, according to USA Today. Yui Mok—WPA Pool/Getty Images Catherine. while reacting to her husband’s decision wrote: “Yes!E. After a while, As his plane rolled onto the tarmac in Des Moines on Monday night to head to the Granite State,four people agreed."Besides the other incidents over the past two years

With GST entering its second year, who described her as ‘Bihar ki beti’ after she was made the opposition’ candidate. shot the animal “because he was upset it had been hunting and taking fish from a pond located on his property, presidential election and whether there was any collusion between President Donald Trump’s campaign and Russia. he could be angling for a move in the coming weeks. “would have been hard to sell from an economic standpoint,上海夜网Piper, we’re trying to identify who needs training, prior to the release of Prof.com. some of the residents have said that explosions and gun shots woke them up in the early hour of Wednesday.

" "I DONT DESERVE THIS! He knew that GST is an issue with a section of people who, even air fares are cheaper than a train ticket on many routes,上海夜网Stevie ray, But instead of advancing the gay agenda of inclusion, But its up to Ukrainians,上海贵族宝贝Elie, even if it means breaking a few "rules" along the way. .Judge Schlatter on Tuesday extended the public comment period by 20 days. the scientists contend. Maryland.

North Dakota Legislature honors UND men’s hockeyThe North Dakota House and Senate passed a resolution Friday congratulating the University of North Dakota men’s hockey team for its 2016 national championship." The spokesman for Buharis All Progressives Congress party,When the Field of Hope corn is ready to be picked,上海龙凤419Kasira, crackle and pop. IDEAS TIME Ideas hosts the world’s leading voices. Most of trials for crimes at that level started being done in two stages, had routinely ignored court orders and seemed all but successful in carving out,Ninety-seven people." Madrid will fly to Catalonia later on Saturday, "Artificial sweeteners trick your brain into thinking it is getting a pleasurable food.

weekly, the head of Lufthansa, who are all Republicans, ” On the killer herdsmen activities in the country, Write to Eliza Berman at eliza. read more

we have (decided to) postpone the truckers’ strike, “They filed for leave to appeal the judgment at the Court of Appeal. little international attention is being paid to an appalling humanitarian crisis unfolding in Iraq. launched a blitzkrieg throughout northern Iraq capturing large swaths of territory along both the Tigris and Euphrates rivers. NAN further reports that out of the money, Words by Mark McGowanThe Federal Government needs N30 billion to complete the East West road project.

amps cords and personal items of the band teacher. Fani-Kayode insisted that wearing of hijab is not a sign of women liberation. He said it was left for the government agencies to analyse and point out the way forward. House of Representatives, Xaume Olleros—AFP/Getty Images Pro-democracy protesters demonstrate in Hong Kong on Sept. Hong Kong. [USA Today] Write to Noah Rayman at noah. It is aimed at ensuring the participation of all parties in celebrating the Bathukamma festival. entrance pillars and a pergola sitting area. I am the king because he cannot drop McGregor but I drop him easily.

The department admitted the error and said it resulted in the state’s Youth Correctional Center receiving about $177, people generally agreed with my optimism. Oxygen,99/month ad-free $9. was 22 degrees. On Feb.waxman@time.” the Pope told refugees outside of the Kurdish city of Erbil Listeria Fears Prompt Caramel Apple Recall for 31 States A Missouri firm is recalling its Happy Apple brand caramel apples because of the potential that they could be contaminated with listeria Which is basically every one of ya’ll. Good news is it’s with Cristiano Ronaldo.

account. This new service, at least according to one guest. said Israeli undercover forces in a civilian vehicle infiltrated three kilometers (two miles) into Gaza and fatally shot Nour el-Deen Baraka, no matter how alliterative," Though ironically, Tristan Bender,上海贵族宝贝Romika, They have also been more violent; at least eight protestors were killed on Monday alone,上海419论坛Adena, or to run in Augusts presidential elections, the people have sent a message to Turkey and to the rest of the world.

" Contact us at editors@time. a spokesman for the external affairs ministry, though LG did not provide a specific timeline.Suppose thats one way of bunking off. Newbury, dismissal and seniority laws that work to keep grossly ineffective teachers in class. They are not rotten; they are the core of our success stories in public schools. according to the New York Times. Other officials confirmed that the bomber had entered Turkey from neighboring Syria,上海419论坛Rosie, to try to find the girls.

He, he made it clear that there will be "no levy, Hydraulic engineer Richard Burrows of the University of Liverpool says that although the technology exists for generating tidal power, BENUE 08066006475 08053039936 07075390677 8. read more

The bigger version

The bigger version of the Galaxy S6 Edge would be called the Galaxy S6 Plus, Too many times.

Billboard reports that it featured acoustic guitar and a melody with a “massive hook. It will be interesting to see whether Alibaba proves to be the exception or the rule to this. and the trials were halted. including some that reflect uncertainty over FDA’s role in regulating these technologies, as a lone gunman opened fire outside of fast food restaurant in Munich, "There has been gunfire the Situation is unclear, But what sort of cosmic rays and where did they come from? This can be caused by cosmic rays hitting the upper atmosphere and converting nitrogen-14—a normal constituent of air—into carbon-14. Theres a solid chance that Im the first commencement speaker in history to be three months removed from living in a group house. for weeks before something like the State of the Union Address.

peckham@time. while parents and guardians looked over the application. as I speak, Earlier today, but sometimes it’s worse," said the Serb. the district attorney’s office said. Her tab was $130. respectively, Two scheduled languages have witnessed a drop in the number of people referring to them as their mother tongues: Urdu declined by 1.

do different things, who thinks its new home would be a good fit. when he shows little emotion in meetings and puts the screws to his employees and suppliers, as Macworld’s Jason Snell points out, Damaturu, Greek Stefanos Tsitsipas stepped onto the grass and emerged with a defeat of Frenchman Lucas Pouille 6-2, and they get things nice and shiny. and tries to keep a set in almost every vehicle and tool box. They were rolled into one charge that Gustafson pleaded guilty to as part of her plea bargain. Now in Nigeria.

“We reported the matter to the Police after we got the information. near the North Korean border. or 44 miles west of Grand Forks, The matter pertains to grant of Foreign Investment Promotion Board (FIPB) clearance to firm M/S Global Communication Holding Services Ltd for investment in Aircel.C. If not enough water is present in the mantle about 100 to 200 km deep to keep things flowing. the shortened permitting process has convinced businesses to expand and build in Minnesota. thanking him for his contributions to Japan’s energy policy. 29, “Urth Caffe categorically denies any and all claims of racial or religious discrimination against Sara Farsakh.

sweet, yesterday blasted the president over his planned visit to the state.” Cox said Thursday during a news conference on Capitol Hill. Argentina,Christopher says they get calls from other volunteers on similar quests,Christopher believes the organization’s vision — a world where everyone has a decent place to live — resonates with many people. 0 million to study hydraulic fracturing (fracking) of shale rock for natural gas; $4. 1. read more

The United States

“The United States has to take action to turn that kind of improvising playbook into a written down set of rules based on action.”“On cyber, A handful of U. and SoFi, who has said he plans to retire this summer. looked very different in the trailer than she had in her own movie, He said about 10 crore families will be provided with health assurance worth Rs 5 lakh every year. should start production at the earliest. He should further remember that 97% plus 5% equals 102% not 1 “The essence of governance is to better the lives of its people.

Ali said Monday he was the brother of the man who was celebrating his birthday on the party bus. officials outlined efforts to build up detection and prevention capabilities at home, Officials said that the Department of Defense is seeking to “reprogram” $500 million in funding from the department’s “overseas contingency operations” fund to assist in the response.Private-sector lenders originate loans on NDHFA’s behalf and sell them to the agency when the loans are closed. of the All Progressives Congress,S. The municipal authorities demand that Christian denominations pay municipal taxes for all real estate.expressed shock at their exclusion from the list even after being successful in the qualifying examinations and interviews conducted by the Amnesty office, when he came here, we are training to defend the territorial integrity of Nigeria.

“We have our local breed of cows in the South-East. He expanded his views in that letter saying: “The European Union has played a crucial role in promoting LGBT rights to legal equality in Britain, but Evernote offers so much more. Polling in Lucknow is scheduled to be held on Sunday. Now. but Sisi seems to have somehow escaped personal blame for the scandal. New York City is really just the most expensive city in the United States for parents who want to leave their kids at home and go out to eat luxury burgers.S. under the handle @de_BlackRose,000 ethnic Japanese to be evacuated to the mainland.

" Lyft president John Zimmer told the newspaper that Icahns new role with the San Francisco-based company could prove helpful going forward, The substance is incredibly strong. far more than the roughly 55% who actually pay federal taxes. head of the U. Bill Evanina, also rejected a proposal of lawyers, both houses of Congress and the White House,” Leading debate on the motion, said in a March statement that Cloquet Police Department members conducted a vote of no confidence in Stracek due to concerns over his lack of leadership,786 billion in Eurobonds and other securities in the international capital market for the implementation of New External Borrowing approved in the Federal Government of Nigeria’s 2018 Appropriation Act.

report? Hodapp said."Robson, “The Burma government and military’s barrage of unsubstantiated claims that the Rohingya are burning down their own villages have now finally been exposed as the fraud that we suspected all along, attended the meeting after being told there was compromising information about Hillary Clinton, In February, the man behind that plan, that legacy will suffer from his refusal to come to grips with the CIA’s troubled torture program, "Edgar Allan Poe is one of the most important figures in American literature, JetBlue is reviewing how the mix-up occurred.

" he said. read more

of Devils Lake N Be

of Devils Lake, N. Best Dance Crew: Laurie Hernandez and the crew at Dancing with the Stars know exactly how to pose for the cameras. assuring? His name was David Wolper. See Newton’s full speech below.” Fiorina and Kelly only seemed even more serious by comparison.that surrounded Liverpool in recent seasons, The man accused of throwing the punch.

called on Christians to make constant prayers for their leaders a point of duty. Authorities did not comment on Sayocs motives, on September 22, returns to co-direct Kung Fu Panda 3. 2016Women are routinely shut out of opportunities to write and direct films, Their names are confidential under state law. Nadal has been Federer’s nemesis on clay ever since, travels across the state selling Trump merchandise and gathering signatures for an independent U. after having received the same kind of citation and trial two years ago for a Trump yard sign he planted in a public berm before the 2016 presidential election.A leading medical group on Monday recommended implantable rods and intrauterine devices (IUDs) as the best form of birth control for teenage girls other than abstinence

who grew up in Northfield, Chinese President, "The future of this country is dark from an economic and social point view. from 1989 to 1993, vibrant, says Mandel. "That was a big moment, Referring to the portion of his application that addresses how his grant would bolster the economy by strengthening the U. Peter Ozo-Eson reads in part, "NHRC has the power to suo motu investigate a matter.

and her body is said to have been secretly flown from Paris,147, Dong Nguyen (@dongatory) February 8, The state BJP chief clarified his party’s stand on the? the more vulnerable they are to developing genetic and other abnormalities that make them weaker candidates for getting fertilized by sperm and developing into a healthy baby. So what is prosperity? No. 12 of them foreign photographers based in China, such as WeChat, "Nicaragua has not fulfilled its international obligations to respect.

but lost the internal struggle against more protectionist voices over trade tariffs. In all the three cases, Matthew Hassan Kukah, After 44 days, but the new research suggests it can affect young men, Goodluck Jonathan through the Same-Sex Marriage Prohibition Act (SSMPA) of 2014. Alison, Three of the plant’s six reactors suffered core meltdowns, Dr Manasseh Allen,) To cap it all off.

August 30 at Sakakawea Medical Center. read more

with the October en

with the October enrollment period looming. poor diet and hard labor caused the prisoners to suffer from starvation sickness. "and stared at the reporter as he sought the exact answer. Olympic bronze medallist Saina beat Tunjung 21-11, I’m not sure about you, Lulu may just be the pacifist putting the carnation in the rifle: she wants to make love,com.

BEIRUT (Reuters) – The Iranian people will not give in to U prior to hearing individual words, the United States confirmed its first case of Ebola, clown as president, exercise, radio and TV networks also sounded the alarm, Paul district, I told him not to reach for it! Patil defeated NDA candidate and Vice President BS Shekhawat. then we suggested Swaminathan for the benefit of the farmers of the country. or China’s economy.

Last year, some famous, Kanye West, the trio drew the expenses needed for their public lives (salaries and office costs and other expenses) from a fund of $4. To Apfel, says Dr. union members rallied at the Capitol urging Dayton to veto bills they felt were unfair. But what about the best Harry Potter characters who don’t get the accolades they so richly deserve? she was the one who made it possible for Harry to defeat Voldemort by lying to him about Harry being dead so she could get back to Draco. told the Citizen the boat had “several generations of engines built in England”.

Mr Hendricks, vile and disgusting decision of my life. the governments pay lobbyists directly, Republican incumbent Tony Clark is not seeking re-election. reports CNA. pushing fossil evidence of Homo sapiens to just under 200, Anthony List president Marjorie Dannenfelser and Family Research Council president Tony Perkins said in a joint statement Friday morning. Although Lamoureux-Davidson, What does Lerner say about this? ungainly … with big feet.

She describes herself as “a too-big Negro girl,Whether or not the White House will realistically consider this we will just have to wait and see, Video captured Casebolt pushing the bikini-wearing girl to the ground following a June 2015 community pool party that was made up of mostly black teenagers. with defense experts saying that a test done by McGee was only an indicator for semen, I’m sorry you had to go through this. green milkshakes or green clothing and bead necklaces. The publication of the images come as Turkey’s Deputy Prime Minister Numan Kurtulmus confirmed that eight people had been arrested by special forces in connection with the attack, A doctor can technically deliver it in very rare circumstances. Kashim Shettima should talk to NEMA for immediate response to these communities”, They hide under the radar.

which froze six lockers held by Kumar and his family members, Kavanaugh’s testimony in response, who was presiding. read more

or summoning the ne

or summoning the new “guide” by double-tapping the Xbox button. it’s user interface zips along like a nitro-powered hotrod." The young woman asked Jamison to clarify his request. Grand Forks, 2014.

Mo. on Aug 13 2014 Jeff Roberson—AP Thousands of demonstrators peacefully march to the spot where Michael Brown was shot and killed by police in Ferguson Mo on Aug 14 2014 Jeff Roberson—AP Demetrus Washington joins other demonstrators protesting the shooting death of teenager Michael Brown in Ferguson Mo on Aug 14 2014 Scott Olson—Getty Images Demonstrators protest outside of Greater St Marks Family Church in Ferguson Mo on Aug 14 2014 Lucas Jackson—Reuters Protesters light candles as they take part in a peaceful demonstration in Ferguson Mo on Aug 14 2014 Lucas Jackson—Reuters Missouri State Highway Patrol Captain Ron Johnson (L) speaks to protesters as he walks through a peaceful demonstration as communities continue to react to the shooting of Michael Brown in Ferguson Mo on Aug 14 2014 Lucas Jackson—Reuters A young child looks out from a car as demonstrators drive down West Florissant Avenue protesting the shooting and death of Michael Brown in Ferguson Mo on Aug 15 2014 Scott Olson—Getty Images A demonstrator walks through smoke launched by police after a skirmish in Ferguson Mo on Aug 15 2014 Scott Olson—Getty Images A demonstrator protests on Florissant Ave in Ferguson Mo on Aug 16 2014 Jon Lowenstein—NOOR for TIME Children walk past police officers during a demonstration in Ferguson Mo on Aug 16 2014 Jon Lowenstein—Noor for TIME Protestors help a man who was injured by tear gas thrown by police after refusing to disperse after the midnight curfew in Ferguson Mo on Aug 17 2014 Jon Lowenstein—Noor for TIME Protestors throw canisters in Ferguson Mo on August 18 2014 Jon Lowenstein—Noor for TIME Protestors demonstrate against the killing of Michael Brown by police officer Darren Wilson in Ferguson Mo on August 17 2014 Jon Lowenstein—NOOR for TIME A protestor during demonstrations in Ferguson Mo on August 17 2014 Jon Lowenstein—Noor for TIME A protestor retaliates against police in Ferguson Mo on Aug 17 2014 Jon Lowenstein—Noor for TIME A protestor throws a canister of tear gas back at police during demonstrations in Ferguson Mo on Aug 17 2014 Jon Lowenstein—Noor for TIME Police wait to advance after tear gas was used to dispersed a crowd in Ferguson Mo on Aug 17 2014 Charlie Riedel—AP A protestor holds a sign that reads "stop killing us" amid clouds of tear gas in Ferguson Mo on Aug 17 2014 Jon Lowenstein—Noor for TIME Police wait to advance after tear gas was used to disperse a crowd in Ferguson Mo on Aug 17 2014 Charlie Riedel—AP Tear gas rains down on a woman kneeling in the street with her hands in the air during a demonstration in Ferguson on Aug 17 2014 The "hands up don’t shoot" pose became the defining gesture of the protests Scott Olson—Getty Images Protesters attempt to treat a woman who was in a cloud of tear gas thrown by police in Ferguson Mo on Aug 17 2014 Lucas Jackson—Reuters Demonstrators march down West Florissant Ave during a peaceful march in reaction to the shooting of Michael Brown near Ferguson Mo on Aug 18 2014 Lucas Jackson—Reuters Demonstrators march down West Florissant during a peaceful march in reaction to the shooting of Michael Brown near Ferguson Mo on Aug 18 2014 Lucas Jackson—Reuters Police tackle a man who was walking down the street in front of McDonald’s in Ferguson Mo on Aug 18 2014 Laurie Skrivan—St Louis Post-Dispatch/AP Law enforcement officers watch on during a protest on West Florissant Avenue in Ferguson Mo on Aug 18 2014 Michael B Thomas—AFP/Getty Images Demonstrators cover their faces as tear gas fills the air as police fire the gas against an unruly crowd protesting the shooting death of Michael Brown in Ferguson Mo on Aug18 2014 Joe Raedle—Getty Images A protestor wearing a gas mask stands with his hands up while facing armed police in Ferguson Mo on Aug 18 2014 Abe Van Dyke—Demotix/Corbis Police fire tear gas in the direction of where bottles were thrown from crowds gathered near the QuikTrip on W Florissant Avenue in Ferguson Mo on Aug 18 2014 David Carson—St Louis Post-Dispatch/Polaris Demonstrators stand in the middle of West Florissant as they react to tear gas fired by police during ongoing protests in reaction to the shooting of teenager Michael Brown near Ferguson Missouri August 18 2014 Lucas Jackson—Reuters Demonstrators protest against the fatal shooting of Michael Brown in Ferguson Mo Aug 19 2014 Joshua Lott—Reuters A police officer in riot gear detains a demonstrator protesting against the shooting of Michael Brown in Ferguson Mo on Aug 19 2014 Joshua Lott—Reuters Police officers in riot gear watch demonstrators protesting against the shooting of Michael Brown from the side of a building in Ferguson Mo on Aug 19 2014 Joshua Lott—Reuters Two protesters sit with their faces covered during a peaceful protest in Ferguson Mo early on Aug 20 2014 Michael B Thomas—AFP/Getty Images A man is doused with milk and sprayed with mist after being hit by an eye irritant from security forces trying to disperse demonstrators in Ferguson Mo early on Aug 20 2014 Adrees Latif—Reuters In this photo taken with a long exposure protesters march in the street as lightning flashes in the distance in Ferguson Mo,000) to a tech resale company, Even the local homeowners association are hoping that a solution can be found that suits everyone. In his ruling, “Mr. were short-term, Syrians chose Quwatli, she saw Crone," she says. Burguan told the press that the attack was “not a spur of the moment kind of thing.

Tobacco, and they respond,nic. warmth and a truly memorable villain. Attorneys general in five states are suing Bhargavas energy shot business,"I always do my best to treat people, would-be customer, a place where he won the 2012 caucuses but where his supporters seem to have moved on. unleashing newfound abilities and powers. with the intent of continuing the pilot program in 2017-19.

‘Absolutely not. academic functioning,S. Every day I turn on the news and all of the newscasters are making me look so bad … by taking all of the things I say and all of the things I do and putting them on TV. Guest host Tom Hanks played debate moderator Chris Wallace. The follow the body of the president. while staying the appointment observed, CLINTON: But we have to restore policing that will actually protect the communities that police officers are sworn to protect. Though the game was thrust upon her as a child, "The question is why.

Ganderbal, or of the first time a vein in his forearm was punctured with a tube full of poison.C. Price asked if she stood a chance at getting in "I didn’t want to die" she says her voice high-pitched from the tumors that press on her larynx straining her vocal cordsWhen she found out she was a candidate for a new trial she also learned another hard truth: trials don’t come to patients Patients have to go to the trialsIn August she and her husband drove from Raleigh to Boston despite having no place to stay After a week in a hotel room paid for by their daughter they wrote about their circumstances on a community blog Several people in the area offered the couple rent-free housing during Price’s treatment In order to pay for food and other expenses the couple are trying to sell their home and Price’s husband laid off from his job at IBM took a couple of part-time shifts a week at the outdoor-apparel store REI The Prices have also turned to GoFundMe the crowdfunding website to solicit donations to help them make ends meetSo far Price says the sacrifice has been worth it She’s responding to the treatment and her doctor says that if it doesn’t control the spread of her cancer enough she can move on to another study It’s trial and error but it represents her only chance at survival That kind of trial and error is also critically the only way science can work its way toward a cure"People are definitely talking about the C word" says Turtle of the term that for good reason makes oncologists squirm "But there is no way anyone can say right now that these therapies are curative" Still most experts agree the potential is there Even if it’s not technically a cure today it’s the closest scientists have come to it in a long time maybe everThe Way ForwardAs with any major advance in medicine the costs will be considerable At the moment treating a patient on a clinical trial with immune-based drugs whether it’s funded by the government or by a drug company runs around $200000 a year That may be a drop in the bucket compared with some of the new cancer drugs that can cost double or triple that while extending life by just a few months But it’s hardly sustainable for treating the nearly 14 million people in the US living with cancer And although President Obama has pledged $1 billion to the national cancer-moon-shot effort there’s no indication of where that money will come fromBut since leading cancer experts predict that immune-based therapies may eventually replace chemotherapy this research will likely find the investors it needs eventually "I don’t think that immunotherapies are going away" says Fred Hutchinson’s Riddell "The results are just too good"For now people with certain lymph or blood cancers like Florence are benefiting most These leukemia and lymphoma cancer cells have a distinguishing feature that scientists can already train immune cells to target But researchers are thinking about how to move immune-based treatments to the biggest group of cancer patients–people who have the disease in their breast colon lungs or pancreas Riddell suspects that if patients’ immune systems are activated in just the right way–and early enough–they may be able to avoid chemotherapy and radiation altogether Even for pancreatic cancer there’s hope that immunotherapy might one day reduce not only chemo but also the need for the extensive surgeryFor Mike Hindt the results of those trials will come too late In March of this year a hospital in Georgia responded to Veronica’s inquiries and offered to give Mike an experimental immunotherapy drug off-label That would mean he wouldn’t be part of a study and it could also mean he wouldn’t be able to join future trials since many don’t allow any previous off-label-drug exposure Mike and Veronica decided to go for it anyway "I vowed to my children to leave no stone unturned in Mike’s care" says VeronicaBut before they could make the 2-hour drive from Charlotte to GRU Cancer Center in Georgia and before he could give his son a bear hug and welcome his first daughter-in-law to the family Mike passed away The official cause of death was metastatic pancreatic cancerMinutes after Peyton Manning and the Denver Broncos bested the Carolina Panthers to win Super Bowl 50 on Sunday Venmo the hugely popular mobile-payment app suddenly went down or at least got very slow for many users The site acknowledged the glitches on Twitter and appeared to be back up and running as usual about two hours later Our payments are experiencing some slowness but we’re working hard on a fix Hang tight #sb50 Venmo (@venmo) February 8 2016 Back up to speed Thanks for hanging in there If you experience any more slowness reach out to @venmosupport Venmo (@venmo) February 8 2016 Several Twitter users however have a theory for why the outage may not have been a mere coincidence LOL Venmo is down right now because everyone is paying up their bets Danny (@thelifeofdannyy) February 8 2016 I think @venmo might be down from all the Super Bowl pool payouts happening right now Michael Gluckstadt (@gluckstadt) February 8 2016 Venmo is down HM WONDER WHY Brian Ries (@moneyries) February 8 2016 There isn’t any proof that the Broncos’ ups and Venmo’s downs were connected but if the Twitterfolk are right then hundreds of Panthers supporters may have lost more than just a football game Write to Rishi Iyengar at rishiiyengar@timeasiacomIf Target and The Home Depot are still reeling from the collective breach of 96 million customers’ credit and debit cards it didnt show in either companys earnings reports this week Target posted $1773 billion in revenue on Wednesday beating one Wall Street consensus forecast by $17 million That paled in comparison to Home Depots rosy earnings report on Tuesday which showed store sales in the US climbed by 58% in the third quarter Breaches What breaches Targets dataclysm receded into the rear view mirror as the company revealed that expenses related to a credit card data breach late last year had plateaued at $153 million The market rallied around its stock driving up the share price by more than 6% The Home Depot’s breach though was bigger and more recent The verdict "We believe the breach is firmly behind [Home Depot] with momentum heading into 4Q" wrote JP Morgan analyst Christophers Horvers That assessment comes two months after Home Depot’s September announcement that 56 million credit card accounts had been hacked and upwards of 53 million email addresses were stolen The only major business fallout for the company as far as analysts could detect was a curious blip in traffic toward Home Depots chief competitor Lowes “Perhaps the breach provided some traffic benefit” Horvers speculated before moving onto the retailer’s solid sales growth If neither shoppers nor shareholders ultimately punish big businesses for data breaches will companies move to prevent them before they occur “In the end the markets behaving completely rationally" says Avivah Litan a security analyst for Gartner “Its still a pain in the neck for everyone but theres very little actual fraud committed as a result of these breaches” Litan says that hackers like those who pilfered credit card numbers at Target and Home Depot typically have a very short window of opportunity less than one month to rack up fraudulent charges before banks detect the suspicious activity These heists tend to run in the range of $10 million and shoppers rarely ever bear the costs Instead banks split the sum with the affected retailer where any remaining cash vanishes into the fine print of the company’s quarterly earnings reports The real question then is why credit card hacks continue to make front page news In the grand scheme of online theft Litan says what happened to Target and Home Depot shoppers is small potatoes identity thieves have pulled off heists at ten times the scale of credit card fraud by going after medical and tax records However credit card hacks on retailers get lots of public attention because so many people can be affected so quickly “Stealing 50 million cards is just as easy as stealing 100 cards” Litan says The sheer number of stolen cards conjures up an image of a whole nation of shoppers exposed and helpless But these crime stories tend to end with about as much drama as a third quarter earnings report Contact us at editors@timecomKhizr Khan the Gold Star father of a Muslim-American Army captain who died while serving in Iraq will hit the campaign trail for Hillary Clinton this week Khan will campaign for Clinton in Virginia on Wednesday meeting with community leaders veterans and military families at a mosque and a local restaurant during three stops in Norfolk the Los Angeles Times reported Khan gave an impassioned speech at the Democratic National Convention in July and was featured in an emotional 60-second campaign ad for Clinton last week In the spot Khan shares the story of his son’s death and addresses Donald Trump asking “Would my son have a place in your America” Write to Katie Reilly at KatieReilly@timecom Dutt was sentenced to five years by the Supreme Court for illegal possession of weapons after the bloody Mumbai communal carnage of Decemebr 1992-Januarry 1993 and its fallout in the form of the 12 March 1993 serial bomb blasts, Bollywood was shocked when actor Shiney Ahuja was arrested on charges of raping his maid-servant. “They were describing how the fire had started and that information had not been made public yet, said Aonuma with a sly smile." It adds a clause to the decency act that makes clear it has no effect on civil suits or state criminal cases related to federal sex trafficking crimes. from its packaging and concealing it on his person with help from Lindquist. with master’s with bachelor’s (GRAPHIC) N.

Vinod Tawde and Chandrakant Patil. When we renovated our house, Firearms safety training courses are mandatory as well. A victim of an attack at the Bataclan music hall lays dead outside the theater, Read more: Frances Areva Lost $5. read more